Skip Navigation
Oklahoma State University
University Research Compliance

A unit in the Division of the Vice President for Research

Biosafety - Toxins Due Diligence

Toxin Due Diligence

PERMISSIBLE TOXIN AMOUNTS

The following select agent toxins are exempt from federal registration and regulations if the amount under the control of a Principal Investigator (PI) does not exceed, at any time, the amounts indicated in the table below.

HHS Toxins [42 CFR Part73.3(d)(3) Amount
Abrin 1,000 mg
Botulinum neurontoxins 1 mg
Short, paralytic alpha conotoxins 100 mg
Diacetoxyscirpenol (DAS) 10,000 mg
Ricin 1,000 mg
Saxiton 500 mg
Staphylococcal Enterotoxins (Subtypes A, B, C, D, and E) 100 mg
T-2 Toxin 10,000 mg
Tetrodotoxin 500 mg

TOXIN DUE DILIGENCE REQUIREMENTS

All OSU PIs in possession of the select agent toxins listed above must maintain a record of all transfers of these toxins outside of their laboratory (i.e., institution name, address, telephone number, and email address). This documentation must include the following:

  • Name and contact information of the recipient;
  • Toxin name and quantity transferred; and
  • Knowledge of recipient’s legitimate need (i.e., prophylactic, protective, bona fide research etc...) to handle or use the toxin.

REPORTING SUSPECTED VIOLATIONS OR SUSPICIOUS ACTIVITY

If an OSU PI detects a known or suspected violation of Federal law or becomes aware of suspicious activity related to a select agent toxin, he or she must immediately notify the OSU Responsible Official or an Alternate Responsible Official using the contact information below. These individuals will then contact the Federal Select Agent Program.

Kenneth Sewell, Ph.D.
Vice President for Research
Responsible Official
203 Whitehurst Hall
kenneth.sewell@okstate.edu
Office: 405.744.6501

Mindy James, Ph.D.
Biological Safety Officer
Alternate Responsible Official
209 Scott Hall
mindymc@okstate.edu
Office: 405.744.3203 or
Office: 405.744.1676

Jennifer Nangle
Assistant Biological Safety Officer
Alternate Responsible Official
208 Scott Hall
jennifer.nangle@okstate.edu
Office: 405.744.3376 or
Office: 405.744.1676

Ashleigh Hall
Biosafety Specialist
Alternate Responsible Official
210 Scott Hall
ashleigh.hall@okstate.edu
Office: 405.744.3736 or
Office: 405.744.1676